Coronavirus and Blood

COVID-19

Coronavirus and Blood: Does coronavirus have direct effects on Blood? The COVID-19 pandemic has become one of the most significant global public health crises in a century. Since its emergence in December 2019, the novel coronavirus (SARS-CoV-2) has infected millions worldwide and caused widespread morbidity and mortality. Beyond its respiratory manifestations, COVID-19 also affects the hematologic system, leading to various […]

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Leishmaniasis

Cutaneous leishmaniasis ulcer on the hand showing inflamed borders and central tissue loss

Leishmaniasis is an infectious disease caused by intracellular protozoan parasites of the Leishmania genus, transmitted to humans through the bite of infected female sand flies. The condition occurs across several endemic regions worldwide and can present in cutaneous, mucocutaneous, or visceral forms. More than 20 Leishmania species are capable of causing human disease; although they appear morphologically similar, they are […]

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Lymphatic Filariasis

Three patients with advanced lower-limb lymphedema caused by chronic filariasis.

Lymphatic filariasis is a mosquito-borne parasitic infection classified as a neglected tropical disease (NTD) and caused by microscopic thread-like filarial worms that reside in the human lymphatic system. This system is essential for maintaining fluid homeostasis and immune defence, and chronic infection can lead to significant lymphatic dysfunction. Transmission occurs when infected mosquitoes introduce larval parasites (microfilariae) into the bloodstream, […]

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Trypanosomiasis

Trypanosomiasis

Trypanosomiasis, also known as sleeping sickness or Chagas disease, is a vector-borne parasitic infection caused by protozoa of the genus Trypanosoma. It affects both humans and animals and is transmitted primarily through the bite of infected tsetse flies (Glossina species) in Africa or by triatomine (kissing) bugs in the Americas. The African form is caused by Trypanosoma brucei gambiense (West […]

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Malaria

Female Anopheles mosquito transmitting malaria parasite during a blood meal

Malaria is a life-threatening parasitic infection caused by protozoa of the Plasmodium genus and transmitted to humans through the bite of an infected female Anopheles mosquito. Once introduced into the bloodstream, the parasite completes a sexual cycle within the mosquito and recurrent asexual cycles in humans, leading to the development of characteristic clinical symptoms. Gametocytes formed in human hosts perpetuate […]

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Human Immunodeficiency Virus

Kaposi Sarcoma on the leg showing multiple violaceous plaques and nodules in an HIV-positive patient

Human Immunodeficiency Virus (HIV) is a major global health concern and remains one of the most significant infectious diseases affecting individuals, communities, and healthcare systems worldwide. HIV is a retrovirus that targets and progressively destroys CD4-positive T lymphocytes, leading to immune dysfunction and increased vulnerability to opportunistic infections and malignancies. Following initial exposure, HIV infection often presents with a transient […]

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Infectious Mononucleosis

Maculopapular skin rash in infectious mononucleosis after amoxicillin treatment, showing widespread erythematous exanthem.

Infectious Mononucleosis (Glandular Fever)—commonly referred to as mono—is an acute viral illness caused predominantly by the Epstein–Barr virus (EBV), a member of the herpesvirus family. First characterised in the 1920s, the infection is transmitted primarily through saliva, earning it the nickname “the kissing disease”, although sharing drinking glasses, utensils, or toothbrushes can also facilitate spread. The incubation period ranges from […]

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