Waldenström’s Macroglobulinemia

Waldenström's Macroglobulinemia

Waldenström’s macroglobulinemia (WM), also known as Lymphoplasmacytic Lymphoma is an indolent B-cell malignancy in which there is a proliferation of small lymphocytes with some plasmacytoid differentiation. The disease is clinically more similar to a lymphomatous disease than to myeloma and other plasma cell disorders. Waldenström macroglobulinemia is one of the malignant Monoclonal Gammopathies. There is usually massive production of monoclonal IgM. […]

Read more

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphomas (NHL) are a heterogeneous group of disorders involving malignant monoclonal proliferation of lymphoid cells in lymphoreticular sites, including lymph nodes, bone marrow, the spleen, the liver, and the GI tract. Most Non-Hodgkin lymphomas (NHL) are B-cell neoplasms though occasionally they are of T-cell lineage. These tumors may result from chromosomal translocations, infections, environmental factors, immunodeficiency states, and chronic […]

Read more

Hodgkin’s Disease

PET Scan

Hodgkin’s Disease (Hodgkin Lymphoma) is a malignant neoplasm that usually arises in a lymph node. It results from the clonal transformation of cells of B-cell origin, giving rise to pathognomonic binucleated Reed-Sternberg cells (RS cells). The nature of the malignant RS cell remains uncertain. Clonally integrated Epstein-Barr virus is present in the RS cells in about 40% of cases. The cause […]

Read more