Hemolytic Disease Of The Newborn (HDN)

Antigen-negative mothers bearing an antigen-positive child are frequently immunized by fetal cells at birth. The number of fetal red cells that enter the maternal circulation can be estimated with the Kleihauer test. In subsequent pregnancies with an antigen-positive fetus, IgG antibodies are formed which cross the placenta and cause hemolysis in the fetus. Most cases of immune HDN are due […]

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