Vascular Bleeding Disorders

Hereditary hemorrhagic telangiectasia HHT with mucocutaneous telangiectasia causing recurrent epistaxis and skin bleeding

Vascular bleeding disorders are a group of conditions in which structural abnormalities of the blood vessel wall result in bleeding manifestations such as easy bruising, petechiae, purpura, and mucocutaneous bleeding. In contrast to platelet or coagulation factor disorders, major or life-threatening hemorrhage is uncommon, with the notable exception of hereditary hemorrhagic telangiectasia (HHT). These disorders arise from inherited or acquired […]

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Hemophilia

Large hematoma bruise symptom of Hemophilia.

Hemophilia is an inherited X-linked bleeding disorder caused by deficiency or dysfunction of clotting factor VIII (hemophilia A) or factor IX (hemophilia B). The impaired coagulation results in prolonged or spontaneous bleeding, particularly into joints and muscles. Hemophilia primarily affects males, while females are typically carriers. The term hemophilia is the standard international spelling (also rendered as haemophilia in the […]

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