CAR T-Cell Therapy

CAR T-cell therapy image showing engineered T cells attacking cancer cells

The mechanism of action of CAR T-cell therapy: T cells: To understand CAR T-cell therapy, it helps to understand what T cells do. White blood cells called lymphocytes play an important part in fighting infection and diseases, including cancer. There are different types of lymphocytes. T cells are one type. T cells move around the body to find and destroy defective […]

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Tumor Lysis Syndrome

Tumor lysis syndrome showing rapid cancer cell breakdown releasing intracellular contents into bloodstream

Tumor Lysis Syndrome (TLS) is a severe and potentially life-threatening oncologic emergency that occurs during or shortly after cancer treatment. It results from the rapid destruction of malignant cells, leading to the release of intracellular contents such as potassium, phosphate, and uric acid into the bloodstream. Tumor Lysis Syndrome is most commonly seen in hematologic malignancies, including leukemia and lymphoma, […]

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Chemotherapeutic Agents

Cell Cycle2

This article reviews the basic principles of chemotherapy for the safe and effective use of various cytotoxic agents. We provide a detailed look at the mechanisms, drug classifications, and standardized regimens necessary for managing neoplastic diseases (cancer). Mastering these foundational concepts is critical for optimizing treatment outcomes and anticipating potential toxicities. Introduction: The long-term understanding of cancer growth is that […]

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Principles of Cancer Therapy

Cancer Therapy

The principles of cancer therapy (which can be curative or palliative) are fundamentally based on the tumor’s characteristics and the patient’s ability to tolerate the treatment. Modern anticancer therapy often includes a combination of modalities like surgery, chemotherapy, immunotherapy, radiation therapy, and/or targeted therapy. Cancer treatment is one of the greatest healthcare concerns globally. Once cancer is confirmed, further diagnostics […]

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