Ask Hematologist | Understand Hematology
Everything you need to know about blood disorders
The mechanism of action of CAR T-cell therapy: T cells: To understand CAR T-cell therapy, it helps to understand what T cells do. White blood cells called lymphocytes play an important part in fighting infection and diseases, including cancer. There are different types of lymphocytes. T cells are one type. T cells move around the body to find and destroy defective […]
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Tumor Lysis Syndrome (TLS) is a severe and potentially life-threatening oncologic emergency that occurs during or shortly after cancer treatment. It results from the rapid destruction of malignant cells, leading to the release of intracellular contents such as potassium, phosphate, and uric acid into the bloodstream. Tumor Lysis Syndrome is most commonly seen in hematologic malignancies, including leukemia and lymphoma, […]
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This article reviews the foundational principles of chemotherapy to support the safe, effective clinical administration of various cytotoxic agents. We provide an in-depth analysis of cellular mechanisms of action, pharmacological drug classifications, and standardized combination regimens essential for the systemic management of neoplastic diseases and malignant tumors. Mastering these core hematology and oncology concepts is critical for optimizing patient treatment […]
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The principles of cancer therapy (which can be curative or palliative) are fundamentally based on the tumor’s characteristics and the patient’s ability to tolerate the treatment. Modern anticancer therapy often includes a combination of modalities like surgery, chemotherapy, immunotherapy, radiation therapy, and/or targeted therapy. Cancer treatment is one of the greatest healthcare concerns globally. Once cancer is confirmed, further diagnostics […]
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