Amyloidosis

Renal Amyloidosis

Amyloidosis refers to a group of rare but serious disorders characterized by the abnormal deposition of amyloid proteins in organs and tissues throughout the body. These insoluble misfolded proteins, produced in the bone marrow, accumulate in vital organs such as the heart, kidneys, liver, and nervous system, impairing their normal function. The ICD-10 code for amyloidosis is E85.9. First described […]

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Multiple Myeloma

Skull X-ray showing multiple lytic bone lesions characteristic of multiple myeloma.

First described in 1848, multiple myeloma (MM)—also called plasma cell myeloma—is a malignant plasma-cell disorder marked by clonal proliferation within the bone marrow and excess production of monoclonal immunoglobulin (M protein). This abnormal expansion disrupts normal hematopoiesis, contributes to bone disease, anemia, renal impairment, and immunodeficiency, and represents one of the most common hematologic malignancies in adults. There are several […]

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