Myelodysplastic Syndrome

Myelodysplasia

Myelodysplastic Syndrome (MDS) is a clonal bone marrow failure disorder characterized by ineffective hematopoiesis, persistent cytopenias, and a variable risk of progression to acute myeloid leukemia (AML). This group of hematologic neoplasms arises when hematopoietic stem cells acquire genetic or epigenetic mutations that impair normal blood cell maturation across one or more lineages—erythroid, granulocytic, or megakaryocytic. The resulting dysplasia leads […]

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