Bispecific Antibodies in Blood Cancers
What Are Bispecific Antibodies and How Do They Work in Hematologic Malignancies? Bispecific antibodies (BsAbs) are engineered immunotherapeutic proteins designed with dual binding specificity. One arm targets a specific tumor-associated antigen on a malignant cell, while the other arm commonly binds the CD3 subunit of the T-cell receptor complex on host cytotoxic T lymphocytes. By physically bridging these two cells, […]
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