Category: Bleeding Disorders

Vascular bleeding disorders are conditions in which abnormalities of the blood vessel wall lead to easy bruising, petechiae, and purpura, but—except for hereditary hemorrhagic telangiectasia (HHT)—rarely cause severe hemorrhage. These disorders arise from inherited or acquired defects that weaken vascular integrity or perivascular connective tissue. Inherited causes include Ehlers-Danlos syndrome, pseudoxanthoma elasticum, osteogenesis imperfecta, Marfan syndrome, and other rare connective […]

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Hemophilia is an inherited bleeding disorder in which the blood fails to clot normally due to a deficiency or dysfunction of specific clotting factors—proteins essential for coagulation. This results in prolonged or spontaneous bleeding, particularly into joints and muscles. The term hemophilia is the standard international spelling (also rendered as haemophilia in the UK and hémophilie, hemofilie, hemofilia, hämophilie, or […]

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