Large Granular Lymphocytic Leukemia

Large granular lymphocytic (LGL) Leukemia is an uncommon condition also described as CD8 lymphocytosis with neutropenia or T-lymphoproliferative disease. The peripheral blood lymphocytosis is composed of cells with round or oval nuclei with moderately condensed chromatin and rare nucleoli, eccentrically placed in the abundant pale blue cytoplasm with azurophilic granules. LGLs comprise 10 to 15 percent of normal peripheral blood […]

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