Megaloblastic Anemias

Introduction: Megaloblastic anemias are a group of disorders characterized by reduced DNA synthesis (not just in red cell series) associated with pathognomonic morphological changes. When DNA synthesis is impaired, the cell cycle cannot progress from the G2 growth stage to the mitosis (M) stage. This leads to continuing cell growth without division, which presents as macrocytosis. The defect in red cell […]






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Iron Deficiency Anemia

Incidence: Over 10% of Western urban populations are iron deficient though not all are anemic. In many other parts of the world, the incidence is still higher. Iron deficiency anemia is particularly common in women of child bearing age. Causes: 1- Poor diet: Foods rich in iron include: Red meat. Poultry. Seafood. Beans. Dark green leafy vegetables, such as spinach. […]






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Anemias-General Approach

Anemia, also spelt anaemia, is usually defined as a decrease in the amount of red blood cells (RBCs) or hemoglobin in the blood. It can also be defined as a lowered ability of the blood to carry oxygen. When anemia comes on slowly the symptoms are often vague and may include: feeling tired, weakness, shortness of breath or a poor ability […]






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Blood Cells

Blood cells fall into three general categories: Red blood cells – Erythrocytes White blood cells – Leucocytes Platelets – Thrombocytes Together, these three kinds of blood cells add up to a total 45% of the blood tissue by volume, with the remaining 55% of the volume composed of plasma, the liquid component of blood. This volume percentage hematocrit is measured […]






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Scope of hematology

Hematology is practiced by specialists in the field who deal with the diagnosis, treatment and overall management of people with blood disorders ranging from anemia to blood cancer. Some of the diseases treated by hematologists include: Anemias e.g. iron deficiency anemia. Polycythemia or excess production of red blood cells. Myelofibrosis. Leukemia. Platelet and bleeding disorders such as hemophilia, idiopathic thrombocytopenic […]






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What is Hematology?

Hematology is a branch of medicine concerning the study of blood, the blood-forming organs, and blood diseases. The word (heme) comes from the Greek for blood. Haematologists investigate, diagnose and treat diseases such as anaemia, leukaemia and lymphoma. They also care for patients with blood-clotting abnormalities and are responsible for ensuring that blood transfusions are safe and available when they […]






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